Emerging Therapies of Multiple Sclerosis
نویسنده
چکیده
5. Monoclonal Anti body Multi ple sclerosis (MS) is a complex immunopathologic disorder of the central nervous system (CNS). For the past several years, there have been six agents approved by regulatory agencies to treat relapsing forms of multi ple sclerosis (MS): interferon beta-1b, intramuscular interferon beta-1a, subcutaneous interferon beta-1a, glati ramer acetate, natalizumab, and mitoxantrone. Phase III registrati on trials and post marketi ng experience have delineated the effi cacy, tolerability, and relati ve safety of these agents. The recent approval of oral fi ngolimod to the MS therapeuti c roster has added a novel agent to our current therapeuti c opti ons, but many additi onal compounds, anti bodies, cell therapies, and treatment interventi ons remain on the horizon.
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